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Carla Edge Oldham, Ph.D.

Carla Edge Oldham
Carla Edge Oldham, Ph.D., Assistant Research Professor
  • Earned BS in Chemistry at Hampton University, Hampton, VA
  • Earned PhD in Biochemistry and Molecular Biology at Purdue University, West Lafayette, IN
  • Worked as a Postdoctoral Fellow at NIEHS/NIH (Laboratory of Signal Transduction), Research Triangle Park, NC
  • Contact: coldham@nccu.edu or 919-530-7728

Research Interests

The focus of my research is the study of signaling pathways and/or signaling molecules and how they might be altered by diseases, such as Alzheimer’s disease and autoimmune diseases and the development of novel drugs to combat these diseases.

  • The Effects of Thyroid Hormone on the Differentiation of Neuronal Cells (collaboration with Dr. Dayami Lopez)
  • Drug repurposing for autoimmune diseases using A query based Approach (collaboration with Dr. Weifan Zheng)

STEM Education/Community Outreach

I am also very passionate about community outreach and STEM education and have participated in planning and implementation of programs that provide hands-on science activities for elementary, middle school, and high school students in after-school programs, summer camps and BRITE Futures at NC Central University. I have also facilitated workshops for middle school and high school STEM teachers to enhance student engagement and learning.


I am currently the executive director of NC STEM ID which is a program that provides a multi-faceted approach to create a STEM identity for students through cross-curriculum professional development opportunities with a STEM focus for middle school and high teachers and STEM engagement opportunities for middle and high school students in Edgecombe, Martin, and Nash counties with NC.


  • Oldham, C.E., Williams, K.P., and Love, L.G. (2015) Undergraduate Research for Students Majoring in Pharmaceutical Sciences Leads to Student Success. In Jeton McClinton et al (Eds). Diversity of Higher Education (Vol. 17, pp. 129-142). Bingley, United Kingdom: Emerald. (ISBN: 978-1-78560-159-0)
  • Yeyeodu, S., Gilyazova, N., Huh, E. Y., Dandepally, S.R., Oldham, C., Williams, A., Ibeanu, G. (2010).  A Trifluoromethyl Analog of Verbenachalcone Promotes Neurite Outgrowth and Cell Proliferation of NeuroScreen-1 Cells.  Journal of Cellular and Molecular Neurobiology 30(7):978– 987.
  • Oldham CE, Mohney RP, Miller SL, Hanes RN, O'Bryan JP (2002). The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination.  Curr Biol. 2002 Jul 9;12(13):1112-6.
  • O’Bryan, J.P., Mohney, R.P., Oldham, C.E. (2001).  Mitogenesis and endocytosis: What is at the INTERSECTIoN?.  Oncogene 20, 6300-6308.
  • Oldham, C.E. (2000) The tyrosine phosphorylation of the CSK-associated protein p62dok in B lymphocytes. Purdue University (e-Pubs)

Related Links

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