Carla Edge Oldham, Ph.D.
Carla Edge Oldham, Ph.D., Assistant Research Professor
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Earned BS in Chemistry at Hampton University, Hampton, VA
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Earned PhD in Biochemistry and Molecular Biology at Purdue University, West Lafayette, IN
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Worked as a Postdoctoral Fellow at NIEHS/NIH (Laboratory of Signal Transduction), Research Triangle Park, NC
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Contact: coldham@nccu.edu or 919-530-7728
Research Interests
The focus of my research is the study of signaling pathways and/or signaling molecules and how they might be altered by diseases, such as Alzheimer’s disease and autoimmune diseases and the development of novel drugs to combat these diseases.
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The Effects of Thyroid Hormone on the Differentiation of Neuronal Cells (collaboration with Dr. Dayami Lopez)
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Drug repurposing for autoimmune diseases using A query based Approach (collaboration with Dr. Weifan Zheng)
STEM Education/Community Outreach
I am also very passionate about community outreach and STEM education and have participated in planning and implementation of programs that provide hands-on science activities for elementary, middle school, and high school students in after-school programs, summer camps and BRITE Futures at NC Central University. I have also facilitated workshops for middle school and high school STEM teachers to enhance student engagement and learning.
NC STEM ID
I am currently the executive director of NC STEM ID which is a program that provides a multi-faceted approach to create a STEM identity for students through cross-curriculum professional development opportunities with a STEM focus for middle school and high teachers and STEM engagement opportunities for middle and high school students in Edgecombe, Martin, and Nash counties with NC.
Publications
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Oldham, C.E., Williams, K.P., and Love, L.G. (2015) Undergraduate Research for Students Majoring in Pharmaceutical Sciences Leads to Student Success. In Jeton McClinton et al (Eds). Diversity of Higher Education (Vol. 17, pp. 129-142). Bingley, United Kingdom: Emerald. (ISBN: 978-1-78560-159-0)
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Yeyeodu, S., Gilyazova, N., Huh, E. Y., Dandepally, S.R., Oldham, C., Williams, A., Ibeanu, G. (2010). A Trifluoromethyl Analog of Verbenachalcone Promotes Neurite Outgrowth and Cell Proliferation of NeuroScreen-1 Cells. Journal of Cellular and Molecular Neurobiology 30(7):978– 987.
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Oldham CE, Mohney RP, Miller SL, Hanes RN, O'Bryan JP (2002). The ubiquitin-interacting motifs target the endocytic adaptor protein epsin for ubiquitination. Curr Biol. 2002 Jul 9;12(13):1112-6.
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O’Bryan, J.P., Mohney, R.P., Oldham, C.E. (2001). Mitogenesis and endocytosis: What is at the INTERSECTIoN?. Oncogene 20, 6300-6308.
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Oldham, C.E. (2000) The tyrosine phosphorylation of the CSK-associated protein p62dok in B lymphocytes. Purdue University (e-Pubs)
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